<P><STRONG>Design and Analysis of Cross-Over Trials</STRONG> is concerned with a specific kind of comparative trial known as the cross-over trial, in which subjects receive different sequences of treatments. Such trials are widely used in clinical and medical research, and in other diverse areas such as veterinary science, psychology, sports science, and agriculture.</P><P>The first edition of this book was the first to be wholly devoted to the subject. The second edition was revised to mirror growth and development in areas where the design remained in widespread use and new areas where it had grown in importance. This new <B>Third Edition</B>:</P><UL><LI>Contains seven new chapters written in the form of short case studies that address re-estimating sample size when testing for average bioequivalence, fitting a nonlinear dose response function, estimating a dose to take forward from phase two to phase three, establishing proof of concept, and recalculating the sample size using condi
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This Element discusses the challenges that different types of corpora offer for the study of pragmatic phenomena. The focus lies on a hands-on approach to methods and data that provides orientation for methodological decisions. We identify areas in which...
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<P>How was it possible for opponents of slavery to be so vocal in opposing the practice, when they were so accepting of the economic exploitation of workers in western factories ¿ many of which were owned by prominent abolitionists? David Brion...
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<p><strong>Statistical Design, Monitoring, and Analysis of Clinical Trials, Second Edition</strong> concentrates on the biostatistics component of clinical trials. This new edition is updated throughout and includes five new chapters.</p><p>Developed...
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This book offers a novel perspective on how people engage in sensing the materiality of the world as a way of social interaction. It proposes a conceptual and analytical advance in how to approach sensing as an intersubjective and interactional phenomenon...
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