Bilde av Molecules Engineered Against Oncogenic Proteins And Cancer Av E. J. (harvard University Cambridge Ma) Corey, Yong-jin Wu
 

Molecules Engineered Against Oncogenic Proteins And Cancer Av E. J. (harvard University Cambridge Ma) Corey, Yong-jin Wu

<p><b>A comprehensive review of the latest molecular advances in cancer treatment</b><p>Featuring 91 total small molecule kinase/KRAS inhibitors, 80 of which are FDA-approved, <i>Molecules Engineered Against Oncogenic Proteins and Cancer</i> documents the recent scientific advances that have transformed one of medicine''s most challenging areas¿cancer treatment. Most of these inhibitors specifically block oncogene-induced carcinogenic proteins with results that have dramatically advanced the treatment of cancer. In addition, the structural formulas of more than 100 kinase/KRAS inhibitors in clinical trials are presented. <p>With a very well-known chemist as an author, <i>Molecules Engineered Against Oncogenic Proteins and Cancer</i> includes information on: <ul><li>Each molecule''s structure, function of the kinase target and relevance to cancer, the drug discovery process, and molecular details of drug action</li><li>Mutated protein kinases as oncoproteins and targets for inhibition,

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