Translational Medicine

<P><EM>Examines Critical Decisions for Transitioning Lab Science to a Clinical Setting<BR></EM>The development of therapeutic pharmaceutical compounds is becoming more expensive, and the success rates for getting such treatments approved for marketing and to the patients is decreasing. As a result, translational medicine (TM) is becoming increasingly important in the healthcare industry ¿ a means of maximizing the consideration and use of information collected as compounds transition from initial lab discovery, through pre-clinical testing, early clinical trials, and late confirmatory studies that lead to regulatory approval of drug release to patients. </P><br/><br/><P><STRONG>Translational Medicine: Strategies and Statistical Methods </STRONG>suggests a process for transitioning from the initial lab discovery to the patient¿s bedside with minimal disconnect and offers a comprehensive review of statistical design and methodology commonly employed in this bench-to-bedside research. </P

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